Online Nutrition Intervention & Corporate Nutrition

Eating, physical activity and other weight-related lifestyle behaviors may have been impacted by the COVID-19 crisis and people with obesity may be disproportionately affected.

Food Is Medicine

Tackling obesity is one of the greatest long-term health challenges the UK faces.

2020 around two-thirds (63%) of adults are above a healthy weight, and of these half are living with obesity. We have 1 in 3 children leaving primary school who are already overweight or living with obesity with 1 in 5 living with obesity.

Obesity is associated with reduced life expectancy. It is a risk factor for a range of chronic diseases, including cardiovascular disease, type 2 diabetes, at least 12 kinds of cancer, liver and respiratory disease, and obesity can impact on mental health

Obesity has become an immediate concern for anyone who is overweight and for our health and care services.

Lots of people who are overweight or living with obesity want to lose weight but find it hard. Many people have tried to lose weight but struggle in the face of endless prompts to eat – on TV and on the high street. In supermarkets, special offers and promotions tempt us to buy foods that are not on the shopping list but are hard to resist. When we eat out, we have little information about how many calories are in the food we are offered. We are biologically programmed to eat and when we are bombarded by advertisements and promotions for food – it’s hard to eat healthily, especially if we are busy or tired or stressed.

Obesity is strongly associated with sickness absence in the workplace. Employees with musculoskeletal and other (chronic) health conditions report higher rates of absenteeism and presenteeism than workers without such conditions. Good nutritional care can improve outcomes for these workers.

Poor nutrition and physical inactivity among employees affect the workplace; overweight and obesity are among the most common health issues affecting productivity .

Workplace health promotion programs to prevent overweight and obesity in office-based employees should be evidence-based and comprehensive and should consider behavioral, social, organizational, and environmental factors.
  • Physical inactivity has increased in workplaces because job roles have changed from manual labor to predominantly inactive tasks.
  • Because of the common use of desktop computers, 45% of employed adults in UK work in sedentary roles
  • Similarly, a rise in levels of automation and in the number of labor-saving devices has resulted in more people working in sedentary roles in the United Kingdom .
  • The combination of sedentary behavior and easy access to energy-dense, nutrient-poor foods compounds the risk of overweight and obesity

Benefits of online NUTRITION intervention

Holistic Nutrition delivered by trained professionals resulted in significant positive changes in both nutrition knowledge and behaviors in participants.

In recent years there has been greater demand from our clients requesting online services and support. Here are some of the benefits of having online nutrition coaching:

  • Greater confidentiality
  • No travel time
  • Feeling safe at home
  • More convenience
  • No waiting rooms
  • Easier to schedule

Increase Your Employees’ Wellbeing & Productivity

Tackling obesity is not just about an individual’s effort, it is also about the environment we live in, the information we are given to make choices; the choices that we are offered; and the influences that shape those choices.

That’s why when it comes to food and drink, we want to ensure everyone has the right information, that they are offered a fair deal and that they are not unduly influenced to purchase less healthy foods and drinks. Put simply, we want the healthy option to be an easier option for everyone.

It’s hard to make the healthy choice if you don’t know what’s in the food you are eating. We know that when shopping, identifying the healthiest products is not always easy. We want to do all we can to help people wherever they shop, to make informed food and drink choices that help them improve their health.

There is growing evidence to suggest that good nutrition is just as important for mental health as it is for physical health and that a number of conditions, including depression, may be influenced by dietary factors(2) Assisting people to effectively manage stress will have a positive
impact on the ability to control both mood and weight.

Mindful Eating

Nutrition interventions works very well alongside other wellness programmes.

The key aspects of a good nutrition intervention include:

  • Employees are involved in planning and delivering the intervention (through needs assessments and/or a team approach such as staff-side
    champions for example);
  • Senior management are consulted on the planning of an intervention as well as being visibly committed to the intervention multi-level approaches work best (for example group workshops alongside changes in the catering provision);
  • Electronic methods are extremely useful in delivering and supporting an intervention, but can be more effective if there is also face to face contact (for example prompts via email following a tasting session, or the provision of an electronic food and drink diary after a question and answer session on the importance of breakfast)
  • physical activity combined with dietary approaches is more effective in weight management than as single components
  • delivery – a mixture of types of activities shows better success rates
  • people do not like being told what to do – behaviour modification strategies are important for behaviour change

A good nutrition intervention in the workplace:

  1. Better business through positive leadership and commitment to health.
  2. Keeping healthy people at work and increasing their productivity potential whilst there.
  3. Working together to achieve a healthy weight for wellness.
  4. Maintaining a healthy environment and culture within the workplace. It is right that workers should take responsibility for their individual healthy habits, but some unhealthy practices can be influenced by the environment. Small ‘nudges’ can create behaviour change and improve health. When implemented by experts using a validated model, behaviour change techniques can be effectively used across organisations to reduce healthcare costs, improve productivity and reduce absenteeism.

Free 15 minute nutrition consultation

  1. Greater London Authority, 2012) http://www.london.gov.uk/sites/default/files/GLA%20
    economics%20 London%27s%20business%20case%20for%20workplace%20health%202012.
    pdf#page=9&zoom=auto,-107,778

2 Long Term Conditions Compendium of Information: Third Edition, Department of Health 2012.

3 Gatineau M, Dent M (2011) Obesity and Mental Health. Oxford: National Obesity Observatory

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Osteoarthritis, full recovery without surgery

Summer, 2016. Osteoarthritis healing.

I woke up with severe pain in my right knee, hence I went to see my GP. After a very short and poorly examination, I was told I do not have anything. I was still naive at that time, hence I trusted him. Why should not trust in my own health care provider? Its there to help us. Unfortunately, they do not provide any real help, They are trained only to prescribe drugs. After few months, pain ceased. Months later, the knee pain moved from the right to left knee. I was leaving with an excruciating pain. My knee doubled in volume, hot on touch, and painful 24/24 h. I went back to my GP, and requested some investigation. Basically, I asked my GP to refer me for Xray, bloods test ( vit D, bone profile, FBC, U&E, and more). I told him about my concerns. He laughed when I said I might have osteoarthritis. However agreed to do all the requested test. Why he did not have any concerns? Because I was not in the high group of risk of the osteoarthritis. I did not have any chronic condition. no smokers, not being overweight.

The results came back. “Osteoarthritis, the knee still well maintained”. I was told, being a degenerative disease, nothing can be done, apart of taking medication for pain management and some physiotherapy exercises. Therefore, I need to wait till I will qualify for a knee replacement. I was very disappointed by the lack of support and compassions from my GP. That moment I realised its not about the health care, everything is about “bad care” (medications, surgery). He did not referred me to the rheumatologist, because nothing could be done. I might try some corticosteroids injections, but in most of the cases do not work .

I was trying to imagine how is going to be my future, how I will be able to work, to leave my life . It was painful to walk, to get off from bed, to look after myself. I was a patient left without any support, hence depression hit me hard.

However, I decided to take my health in on my hands, and refuse to leave with pain and being unhappy.

Ironically, at the time. I was working in an elective surgical orthopaedic ward. All the patients admitted for knee/hip replacement due to osteoarthritis deterioration (bone to bone). I started to do my own research throughout the patients. None of them had the vitamin D checked. None of them have any properly investigation. However, everyone has been told osteoarthrtis is degenerative disease. There is not cure, they need to learn to leave with the pain, and wait for knee/hip replacement. I encountered patients with double knee replacement, and people who completely have knees and hips replaced, also shoulders.. I was shocked. Those people practically became “human robots”.

This was my moment of Enlightenment.

I wrote my own treatment plan ( vitamin D level it was incredible low), detox diet, taking professional multivitamins and minerals. I changed my diet, even though my diet was not so bad, for my high level of inflammation was not good. Hence I avoid all the foods with a high risk of inflammation, following an anti-inflammatory diet, I went back to school and I did herbal medicine.

Another Enlightenment moment: Gaia, the powerful Mother Earh

I realised I have been suffering of “plant blindness”

A phenomenon called “plant blindness” means we tend to underappreciate the flora around us. That can have disastrous consequences not only for the environment, but human health.

Herbal medicines are made from plants. I learnt how to use combinations of plant parts, leaves, flowers or roots. Each part of the plant can have a different medicinal use. Since than I have been using dried plants to make the medicine, also recommended to my clients.

Herbal medicine aims to restore the body, so that it can protect, regulate and heal itself. It is a whole body approach. It looks at your physical, mental and emotional well being.

Plants are incredible powerful. One of my favourite is the delicate dandelion.

The practice of using herbal supplements dates back thousands of years.  I learnt how to make tinctures, gels, lotions, or creams, and I am using them to treat my clients for various conditions such as allergies (asthma, hay fever, sinusitis etc) , skin problems, constipations, to heal the liver and more.

Hence, I managed to completely recover my knees through nutrition, vitamins and minerals, collagen, herbal creams, body and mind detox and osteoarthritis knee exercises.

6 months later I went back to see my GP to request another blood test and Xray. My GP refused to do another Xray,

He asked me: “If I feel so good why do I want to expose myself to radiations? Fair enough I said :), However, I was not asked how did I managed to completely recover from osteoartrathitis. It was my confirmation how ” sick is the health care system”.

I am free of pain, and enjoying my life <3

Madelena Tapliga

MSc Clinical Nutritionist, accredited Nutritionist of UK from Association for Nutrition (AfN) London

Herbal Medicine

MLD therapist

To schedule an appointment, call 07947887043 or click here to use our online form.

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Clinical nutritionists use a holistic approach to healing, taking into consideration the whole person, mind, body and soul. This approach is evidence-informed, meaning research findings and traditional medicine knowledge are combined to inform treatments plans.

Clinical nutritionists recognise that disease is complex and is caused by a combination of factors. As a result, clients are given individualised care in response to their health. They help prevent and treat chronic diseases — such as obesity, heart disease and diabetes 

According to The European Society of Clinical Nutrition and Metabolism (ESPEN), Clinical Nutrition is defined as ‘a discipline that deals with the prevention, diagnosis and management of nutritional and metabolic changes related to acute and chronic disease and conditions caused by a lack or excess of energy and nutrients’.

Clinical nutrition and health

Clinical nutrition involves a good understanding of what nutrients are necessary for your body to function and how what you eat affects your health. A clinical nutritionist is concerned with how nutrients in food are processed, stored and discarded by your body, along with how what you eat affects your overall well-being

  • clinical nutrition

 Poor diet can be linked to a number of physical ailments, and even mental health problems. An unhealthy diet, for example, can increase the risk of at least 13 types of cancers, cause tooth decay and depression, and has even been found to cause more deaths than smoking. Still, it’s important to note that both hunger and obesity are forms of malnutrition. Eating nourishing foods can ward off illness and improve overall quality of life.

Nutrition assessment

Nutritionists evaluate their clients’ health through nutrition assessment and, in some cases, diagnostic laboratory testing. Based on their findings, they can advise their clients on how they should modify their behavior, develop meal and nutrition plans for their clients, and counsel their clients on their nutritional needs. Nutritionists help prevent or treat health conditions including heart disease, autoimmune diseases, and obesity. They may also work with clients who suffer from disordered eating.

A clinical nutritionists consider food in terms of nutrient value and how those nutrients affect functions of the body. By testing a sample of a patient’s blood or urine, the practitioner can detect any imbalances in the body. A common example of an imbalance is high cholesterol.

A clinical nutritionist focuses on the cause of the imbalance, a doctor is trained to prescribe drugs.

Clinical nutrition and biochemical individuality

A general theory behind the science of clinical nutrition is called biochemical individuality. The theory was first introduced by biochemist Dr. Roger Williams in the 1950s. Biochemical individuality theory claims that because each human body is biochemically unique, each has his or her own specific nutritional needs.

Many common symptoms can arise from nutritional imbalances, such as headaches, fatigue, and nausea. A clinical nutritionist can determine what is causing the imbalance and structure a diet to restore balance and relieve symptoms. They not only look at how food affects the digestive track, but attention is also given to how diet affects the immune system and brain wave function. The theory is that the mind and body are connected and diet affects them both

In many cases, nutritionists work as members of larger patient care teams, collaborating with physicians and other healthcare professionals.

Madelena Tapliga

MSc Clinical Nutritionist, accredited Nutritionist of UK from Association for Nutrition (AfN) London

Herbal Medicine

MLD therapist

To schedule an appointment, call 07947887043 or click here to use our online form.

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Your email address will not be published.

Why Personalised Nutrition

Because YOU are at the centre of personalised care for improved wellbeing

Poor diet and lack of physical activity (PA) are major risk factors for non-communicable diseases (NCDs) including type 2 diabetes (T2D), cardiovascular diseases (CVDs) and many cancers. Up to 80% of major CVDs, and over one-third of cancers, could be prevented by eliminating shared risk factors, including tobacco use, unhealthy diet, physical inactivity and excess alcohol consumption. This emphasizes the importance of changing lifestyle in public health initiatives. Despite the known link between dietary patterns and disease, interventions to alter dietary habits and to improve public health and wellbeing have had limited impact. Personalisation of interventions can be more effective in changing behaviour that will affect health outcomes.

Personalised nutrition and individually tailored nutrition mean similar things and go a step further by attempting to deliver nutritional intervention/advice suited to each individual

Nutrigenetics is an aspect of personalised nutrition that studies the different phenotypic responses (ie, weight, blood pressure, plasma cholesterol, or glucose levels) to a specific diet (ie, low fat or Mediterranean diets), depending on the genotype of the individual

• Nutrigenomics involves the characterisation of all gene products affected by nutrients and their metabolic consequences. 2003 UK Department of Health whitepaper forecast that with increased knowledge of genetics, “treatment, lifestyle advice, and monitoring aimed at disease prevention could then be tailored appropriately to suit each individual”. The establishment of pan-national organisations such as the European Nutrigenomics Organisation (NUGO) and the International Society for Nutrigenomics & Nutrigenetics have further served to increase the infrastructure and international collaboration around nutrigenomics research. Given the increasing global burden of nutrition-related noncommunicable diseases , Nutrigenomics could help to develop more sustainable approaches to encouraging dietary change at a population-level.

• Exposome is the collection of environmental factors, such as stress, physical activity and diet, to which an individual is exposed and which may affect health

Epigenomics is a branch of genomics concerned with the epigenetic changes (methylation, histone modification, microRNAs) that modify the expression and function of the genetic material of an organism

• Metabolomics is the scientific study and analysis of the metabolites (usually restricted to small molecules, ie, <900 daltons) produced by a cell, tissue, or organism

• Microbiomics is the study of the microbiome, the totality of microbes in specific environments (ie, the human gut)

  • Personalised nutrition is tailored specifically for you

The overall goal of personalised nutrition is to preserve or increase health using genetic, phenotypic, medical, nutritional, and other relevant information about individuals to deliver more specific healthy eating guidance and other nutritional products and services.

Personalised nutrition is equally applicable to patients and to healthy people who may or may not have enhanced genetic susceptibilities to specific diseases.

Personalised nutrition can be applied in two broad areas: firstly, for the dietary management of people with specific diseases or who need special nutritional support—for example, in pregnancy or old age, and, secondly, for the development of more effective interventions for improving public health. Individuals may also wish to use personalised nutrition to achieve personal goals/ambitions that are less directly related to health—for example, to deal with preferences for, and dislikes of, specific foods, to attempt to achieve a desired body size or shape, or for competitive sports

What are the conceptual bases for personalised nutrition?

Personalised nutrition is based on the idea that individualising nutritional advice, products, or services will be more effective than more generic approaches.

Personalisation can be based on:

  • Biological evidence of differential responses to foods/nutrients dependent on genotypic or phenotypic characteristics
  • Analysis of current behaviour, preferences, barriers, and objectives and subsequent delivery of interventions, which motivate and enable each person to make appropriate changes to his or her eating pattern.

Key messages

  • Personalised nutrition uses information on individual characteristics to develop targeted nutritional advice, products, or services to assist people to achieve a lasting dietary change in behaviour that is beneficial for health
  • Personalised nutrition is based on the concept that individualised nutritional advice, products, or services will be more effective than more traditional generic approaches
  • This personalisation may be based on biological evidence of differential responses to foods/nutrients dependent on genotypic or phenotypic characteristics, and/or based on current behaviour, preferences, barriers and objectives

More about Personalised nutrition and health | The BMJ

Madelena Tapliga

MSc Clinical Nutritionist, accredited Nutritionist of UK from Association for Nutrition (AfN) London

Herbal Medicine

MLD therapist

To schedule an appointment, call 07947887043 or click here to use our online form.

Currently, Astaxanthin (ASX) is a renowned compound for its commercial application in various industries comprising aquaculture, food, cosmetics, nutraceuticals, and pharmaceuticals.

95% of ASX available in the market is produced synthetically using petrochemicals due to cost-efficiency for mass production.

Safety issues have arisen regarding the use of synthetic ASX for human consumption, while the ASX derived from H. pluvialis is the main source for several human applications, including dietary supplements, cosmetics, and food

Astaxanthin possesses an unusual antioxidant activity which has caused a surge in the nutraceutical market for the encapsulated product. Also, health benefits such as cardiovascular disease prevention, immune system boosting, bioactivity against Helycobacter pylori, and cataract prevention, have been associated with astaxanthin consumption

ASX is more bioactive than zeaxanthin, lutein, and β-carotene.

ASX has unique features that support its potential use in promoting human health.

ASX preserves the integrity of cell membranes by inserting itself in their bilayers, protects the redox state and functional integrity of mitochondria, and demonstrates benefits mostly at a very modest dietary intake, since its strongly polar nature optimizes the rate and extent of its absorption. Recently, ASX has attracted considerable interest because of its potential pharmacological effects, including anticancer, antidiabetic, anti-inflammatory, and antioxidant activities as well as neuro-, cardiovascular, ocular, and skin-protective effects, and achieve effective skin cancer chemoprevention

Astaxanthin decreased oxidative stress and inflammation and enhanced immune response
in humans

Immune cells are particularly sensitive to oxidative stress due to a high percentage of polyunsaturated fatty acids in their plasma membranes, and they generally produce more oxidative products. Overproduction of reactive oxygen and nitrogen species can tip the oxidant:
antioxidant balance, resulting in the destruction of cell membranes, proteins and DNA. Therefore, under conditions of increased oxidative stress (e.g. during disease states), dietary antioxidants become critical in maintaining a desirable oxidant: antioxidant balance.

This study showed a dietary astaxanthin decreases a DNA damage biomarker and acute phase protein, and enhances immune response in young healthy females.

Anti-inflammatory Benefits

Promotes Integrated Immune Response

Effects on Metabolic Syndrome

Effects on Circulation.

As people age, their red blood cells (RBCs) can be more susceptible to oxidative attack, resulting in peroxidative damage to the RBC membrane phospholipids,31 impairing its oxygen-carrying capacity.

Preliminary Benefits for Memory and other Higher Brain Functions .Astaxanthin might improve cognitive functions

Effect on Vision and Eye Fatigue .

Astaxanthin has been extensively researched for its benefits for vision, especially in Japan.

Astaxanthin also might relieve eye fatigue in persons using computer monitors. Extended work at computer monitors is linked to eyes strain and to blurred vision, often accompanied by tensing of the muscles of the shoulder and low back.

Muscle Performance and Endurance

Effect on Helicobacter pylori in Functional Dyspepsia


In a 2008 RCT, astaxanthin was evaluated for functional dyspepsia (FD).

Effect on Mitochondrial Function

In a series of experiments with various cultured cell lines astaxanthin improved cell survival under oxidative stress (from the addition of antimycin A, which increases mitochondrial ROS generation). By adding an oxidant-sensitive molecular probe into the mitochondria, the researchers found that astaxanthin reduced the mitochondria’s endogenous production of oxygen radicals and protected the mitochondria against a decline of membrane
function that typically occurs over time in these cultures. Astaxanthin’s positive activity went even further; it increased mitochondrial activity in these cells by increasing oxygen consumption without increasing generation of ROS.

Skin-Protective Mechanisms of Astaxanthin

2.1. Antioxidant Activity

Oxidant events of skin aging involve damage to DNA, the inflammatory response, reduced production of antioxidants, and the generation of matrix metalloproteinases (MMPs) that degrade collagen and elastin in the dermal skin layer . There are many dietary or exogenous sources that act as antioxidants, including polyphenols and carotenoids.

ASX has recently caught the interest of researchers because of its powerful antioxidant activity and its unique molecular and biochemical messenger properties with implications in treating and preventing skin disease. Comparative studies examining the photoprotective effects of carotenoids have demonstrated that ASX is a superior antioxidant, having greater antioxidant capacity than canthaxanthin and β-carotene in human dermal fibroblasts.

In skin, ASX has been shown to improve dermal health by direct and downstream influences at several different steps of the oxidative stress cascade, while inhibiting inflammatory mediators at the same time [12]. Molecular and morphological changes in aged skin not only compromise its protective role, but also contribute to the appearance of skin symptoms, including excessive dryness and pruritus, as well as increased predisposition to the formation or deepening of wrinkles, dyspigmentation, fragility and difficulty in healing injuries, alteration in skin permeability to drugs, impaired ability to sense and respond to mechanical stimuli, skin irritation, and tumor incidence . The effects of ASX on hyperpigmentation suppression, melanin synthesis and photoaging inhibition, and wrinkle formation reduction have been reported in several clinical studies

2.2. Anti-Inflammatory Properties

2.3. Immune-Enhancing Effects

Activated T cells and NK cells produce interferon-γ (IFN-γ), which is involved in immune regulation and B cell differentiation; Therefore, ASX can enhance immune responses and potentially exert antitumor activity

2.4. Effects on Skin Damage

2.5. Effects on DNA Repair

Absorption

Astaxanthin ’s bioavailability is substantially affected by meal timing and by smoking.

Astaxanthin produces clinically significant antioxidant benefits in humans, including people vulnerable to oxidative stress, such as smokers, the obese, and the overweight.

Can be ordered here. 100% pure Astaxanthin 17.5 mg/50 g in organic manual pressed olive oil

Madelena Tapliga

MSc Clinical Nutritionist, accredited Nutritionist of UK from Association for Nutrition (AfN) London

Herbal Medicine

MLD therapist

To schedule an appointment, call 07947887043 or click here to use our online form.

references

Higuera-Ciapara, L. Félix-Valenzuela & F. M. Goycoolea (2006) Astaxanthin: A Review of its Chemistry and Applications, Critical Reviews in Food Science and Nutrition, 46:2, 185-196, DOI: 10.1080/10408690590957188

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What is DMSO? It is a natural chemical compound derived from pine trees as a byproduct from the manufacturing of paper. It is composed of two methyl groups (CH3) and a sulfur and an oxygen atom.

It is also found naturally in garlic as one of garlic’s 70+ sulfur compounds.

DMSO builds up the white blood cells and increases immune production of migration inhibitory factors (MIF) by macrophages.

DMSO has been associated with a number of therapeutic benefits, such as for the healing of wounds; its use as an anti-inflammatory, anti-bacterial, anti-viral, and anti-fungal; softens collagen, helps eliminate hydroxyl free radicals in the body, stimulates the immune system, increases interferon formation, reduces the number of platelet thrombi, and is a potent diuretic. DMSO skin remedies are useful in treating topical fungal infections.

DMSO, or dimethyl sulfoxide, has been used for many years by athletes to treat painful muscles and joints

DMSO has been described by Dr. Jacob as a new medical principle.

Why is organic sulphur so important?

Sulphur: The Stuff of Life

Every living cell, plant or animal, contains sulphur. Given that the human body is a collection of trillions and trillions of cells, if we want to have a happy body – we first have to have happy cells.

Since organic sulphur plays an essential role in the oxygenation and detoxification of all living things…..you could say without fear of contradiction, that it is the key to life

Why is DMSO so effective?

Sulfur compounds are found in all body cells and are indispensable. They are needed for a number of chemical reactions involved in the detoxification of the body. As a source of sulfur, DMSO aids in heavy metal detoxification. Sulfur binds with toxic heavy metals (mercury, lead, aluminum, cadmium, arsenic, nickel) and eliminates them via urination, defecation and sweating. DMSO protects the cells from mechanical damage and considerably less amounts of it is needed to achieve results compared to many other pharmaceutical drugs. This is a crucial mechanism since some molecules in our bodies produce an unequal number of electrons and the instability of the number causes them to destroy other cells. DMSO hooks on to those molecules and they are then expelled from the body. DMSO is an effective pain killer, blocking nerve conduction fibers that produce pain and reduces inflammation and swelling by eliminating inflammatory chemicals.

It also has a calming effect on the central nervous system and it reaches all areas of the body, when absorbed through the skin, including the brain.

What is Methylsulfonylmethane ?

Methylsulfonylmethane, commonly called MSM, is a product that is derived from DMSO. MSM has many of the properties of DMSO, but is generally regarded as a food supplement. It has not been subject to the medical studies of DMSO and is not considered to be as effective as DMSO in treating most ailments. However, it also does not cause the patient to have the garlic-like
DMSO breath.

What is DMSO ?

DMSO is one of the most powerful free radical scavengers known. Free radicals are unstable charged molecular fragments that attack other molecules causing severe damage to cells throughout the body. This disrupts the normal functioning of various organs in the body. Free radical damage is usually slow and accumulates over the years. Eventually this can lead to such ailments as cancer and arthritis. It can also lead to premature aging. It is possible that the
regular use of DMSO may completely prevent some serious ailments.

Another important action of DMSO is its immune normalizing effect. This makes DMSO important in the treatment of autoimmune diseases and can also help the natural immune system fight off various infectious and contagious diseases.
DMSO also passes through the skin and other cellular membranes of the body.
This is the reason that the application of a small amount of DMSO applied topically to the skin can cause a garlic like breath odor. DMSO is one of the the products that are able to cross the blood brain barrier. It is also able to take other products that normally do not cross this barrier with it. This could make DMSO valuable in the treatment of many brain problems.
Another important action of DMSO is it is a vasodilator. This can increase blood flow, allowing blood to more easily reach areas where damage may have occurred. Often an injury causes decreased blood flow to the injury site, and some of the damage is caused by the lack of blood to the area after the injury, and not just the injury itself.
In many cases DMSO is used to treat one problem, and it ends up helping a completely unrelated health problem.

Benefits of DMSO (Organic Sulphur)

DMSO can help with a number of different issues and conditions. This includes all of the following:

Inflammatory diseases

  1. DMSO for Pain

DMSO is known to address a variety of types of pain. Strains and sprains are one type of pain that DMSO can address. When used topically, DMSO can eliminate the pain of these types of injuries. DMSO will pass through the skin’s oily membranes and reduce swelling and inflammation in the area. DMSO can also be effective for pain related to bruises, burns, scars, and keloids. A concentration of 50 to 80 percent DMSO put on two to three times per day can flatten a raised scar and eliminate burns and bruising.

Carpal tunnel syndrome.

Carpal tunnel syndrome is the most commonly reported repetitive strain injury in the workplace. It is caused by compression of the median nerve which results in neuropathy of the nerve. The median nerve is the nerve in the wrist that supplies feelings and movement to parts of the hand. The compression of the median nerve can lead to numbness, tingling, weakness, or muscle damage to the hands and fingers. Long term carpal tunnel syndrome can lead to permanent nerve damage and atrophy of some of the muscles in the hands and fingers.
The conventional treatment has been night splints and cortisone injections. Various anti-inflammatory drugs have also been used. When all else failed, Surgery was used to cut the transverse carpal ligament. Surgery has resulted in mixed results. Some patients have found that surgery actually made the condition worse.
Some patients who tried various drugs and even surgery have reported dramatic results with the use of DMSO. Others have reported similar results with MSM (methylsulfonylmethane),

DMSO for Burns. Skin lotions containing DMSO have proven effective in treating burns.

Diabetes. and DMSO

DMSO has shown great potential in treating diabetic neuropathy. This is often a major problem in older people who have suffered from diabetes for many years. DMSO improves the blood supply by dilating the small blood vessels thereby increasing circulation to the extremities. DMSO should be part of the normal medical treatment of every diabetic. The treatment should not wait until there is a major circulation problem where amputation is considered. Prevention of the problem should be the goal. It is probable that most diabetic related amputations could be prevented with routine DMSO treatment for all diabetics

  • Cancer side-effects (pain)
  • Gastrointestinal disorders
  • Headaches and migraines
  • Fibromyalgia
  • Shingles
  • Psoriasis
  • Candida
  • Eczema
  • Tendonitis
  • Arthritis
  • Interstitial cystitis
  • Autoimmune disorders
  • Muscle spasms
  • And more!

Dimethyl sulfoxide (DMSO) is currently used as an alternative treatment for various inflammatory conditions as well as for cancer. In this study (Elisia et al. 2016) was demonstrated that DMSO has ex-vivo anti-inflammatory activity using Escherichia coli(E. coli) and herpes simplex virus-1 (HSV-1)-stimulated whole human blood. Specifically, we found that between 0.5%– 2%, DMSO significantly suppressed the expression of many pro-inflammatory cytokines/chemokines and prostaglandin E2 (PGE2).

In this study, was demonstrated that both DMSO and DMS represent strong anti- inflammatory properties by blocking constitutive as well as IL-1β-induced IL-6 and IL-8 expression in the human chondrocyte cell line C-28/I2

How to use DMSO:

DMSO is generally applied to the skin in a gel, cream, or a liquid. It can be taken orally but this should only be for more severe internal detoxification. We recommend to order click here  DMSO available in both liquid and gel form.

Contra-indications:

DMSO is a carrier and it opens cell membranes.

In short – it will enhance the performance of any medication or natural therapeutics (e.g. Nutritional supplements, herbal remedies etc) you currently take.

This is not a down side if your goal is to reduce or stop any dependency on drugs, but it is something you (and your health professional) should be aware of and understand before embarking on its use.

It may be especially important to monitor blood sugar levels, liver/kidney function or hormone levels (e.g thyroxin) more frequently if you have any pre-known conditions.

People taking blood thinners should not use DMSO.

Allergic reactions are rare. Introduce DMSO with a skin test on a small portion of skin to make sure it’s safe for you to use.

DMSO also causes a garlic-like taste in the mouth – this is quickly remedied by brushing your teeth after use.

If you are pregnant, nursing, taking medication, or have a medical condition, consult your health care professional before using products based on this content.

How can you order?

click here call 07947887043 or [email protected]

100ml of Super Pure Happy Health grade DMSO ( Dimethyl Sulfoxide ) Supplied in a glass bottle. This has 70% pure DMSO and 30% pure distillate water and is manufactured to an exacting quality standard for the synthesis of Active Pharmaceutical Ingredients ( API ) It is one of the purest forms of DMSO available and should not to be confused with cheaper Industrial grades or DMSO manufactured in China.

Madelena Tapliga

MSc Clinical Nutritionist, accredited Nutritionist of UK from Association for Nutrition (AfN)

Herbal Medicine

MLD therapist

To schedule an appointment, call 07947887043 or click here to use our online form.

Have your say about what you just read! Please leave us a comment in the box below.

References

1 Elisia, I., Nakamura, H., Lam, V., Hofs, E., Cederberg, R.A., Cait, J., Hughes, M.R., Lee, L., Jia, W.W., Adomat, H.H., Guns, E.S., McNagny, K.M., Samudio, I.J., & Krystal, G. (2016). DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis. PLoS ONE, 11.

The content on our website and in our online courses is for educational purposes only. 

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  1. Hi! My name is Simona, I bought some products includind DMSO kit from Maddie for me and my daughter. DMSO is life changing
    She dedicated her time and patience so as to get the right products for me.
    I would highly recommend you Maddie, you are very knowledgeble and your products are fantastic.

    Reply

  2. Hi, my name is Vasile, I know Madie for few years, I am passionate about health life style as she is, I bought few great products from her in the past and they are amazing. I was back from Romania in Uk and after few days, I started to have a very bad flu, headache, flu, cough, sneezing, I contacted Madie and told about that, she gave me two great products, one product is not very taste, but with juice or lemon goes very well. The name of the product is DMSO. After 2 days, I started to feel better and build my strength and have more energy, I mange to take no tablets at all in this time.
    I am nurse, on my feet 12 h long shift, loking after sick patients.
    I have energy, and I do not have any post covid symptoms

    Thank you for Help Miss. Madie

    Reply
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Knee to toes. What you need to know

Management of Varicose Vein

Varicose veins are twisted, dilated veins most commonly located on the lower extremities. Risk factors include chronic cough, constipation, family history of venous disease, female sex, obesity, older age, pregnancy, and prolonged standing. The exact pathophysiology is debated, but it involves a genetic predisposition, incompetent valves, weakened vascular walls, and increased intravenous pressure. A heavy, achy feeling; itching or burning; and worsening with prolonged standing are all symptoms of varicose veins. Potential complications include infection, leg ulcers, stasis changes, and thrombosis. Some conservative treatment options are avoidance of prolonged standing and straining, elevation of the affected leg, exercise, external compression, loosening of restrictive clothing, medical therapy, modification of cardiovascular risk factors, reduction of peripheral edema, and weight loss. More aggressive treatments include external laser treatment, injection sclerotherapy, endovenous interventions, and surgery. 

Why legs matter

Our legs and feet do a lot for us but often they do not get the attention they deserve. Its really important that we keep an eye on our lower legs and feet. Even the smallest change to the way they look or feel can be a sign of something more serious.

The little things normal for

According to one of observational study (2019) Patients with chronic venous leg ulcers showed significantly higher BMI, hyperhomocysteinaemia, and higher levels of serum copper but significantly lower levels of vitamin B6, B9 and C, as well as a significantly lower level of zinc. Vitamin D deficiency was present in both groups, however, severe vitamin D deficiency was present only in the leg ulcer group. Mobility was significantly reduced in patients with leg ulcers.

Conclusion: Ulcer patients are often obese but suffer from qualitative malnutrition, including a lack of vitamin D, which might be explained by reduced mobility and being housebound. Hypoalbuminaemia, as a sign of protein deficiency, was observed significantly more often in patients with chronic leg ulcers, irrespective of wound area or wound duration.

This idea of a nutritional approach should be integrated into the therapeutic strategy of any wound, especially in elderly patients. In fact, age, with the associated decrease in taste and appetite, as well as problems with chewing, is a major risk factor for malnutrition. Malnutrition results not only from low calorie intake, but also from a lack of micronutrients. In other words, obesity, which is so common in our patients with leg wounds, can be accompanied by a nutritional deficit due to a diet poor in vitamins and essential amino acids. Patients who live alone, suffer from depression or have little mobility for shopping and preparing food are also at risk of malnutrition.

Interestingly, there is an overlap of risk factors for malnutrition and venous ulcers: age, obesity, social isolation, depression, poor mobility. And it is in a vicious circle, so a psychosocial approach is essential for the holistic treatment of these patients.

Nutrition is important for vein health

Chronic venous insufficiency and varicose veins appear to be related to an obesity-promoting Western lifestyle poor in dietary fiber and low in physical activity. Evidence suggests that avoidance of these risk factors may reduce the incidence of venous disorders.

High-Fiber Diets

Foods High in Rutin

Many specialists agree that the best foods for varicose veins are those high in rutin. The miraculous flavonoid has an array of benefits that has many effects on the body. One of the most essential is the ability to strengthen capillaries that are weak and most apt to develop varicose veins. As well, rutin is a vasoprotective (protects of blood vessels), anti-inflammatory, antithrombotic, (protect against blood clots) and antioxidant. Natural sources of rutin are apple, buckwheat, grapes, cherries, apricots and blackberries.

Avoidance of Overweight

Botanical Treatments

Horse chestnut seed (Aescin). The active component (aescin) appears to promote blood circulation and may strengthen the elasticity of veins. The common dosage of horse chestnut is 300 mg twice daily, containing 50 mg of Aescin in each dose.

Evidence suggests that venous insufficiency and varicose veins may be, in part, preventable through a high-fiber, low-fat diet; regular exercise; and maintenance of normal body weight. Medical, surgical, and botanical approaches are available for treatment.

Risk Factors

Family history. 90% risk of developing varicose veins if both parents have varicose veins, but less than a 20% risk if neither parent is affected.[1],[2]

Female gender. Venous insufficiency and varicosities occur up to twice as often in women as men.

Tall height. The association with height is thought to be due to the effect of gravity and pooling of blood in the lower extremities.

Advanced age.

Previous venous damage. History of leg injury, phlebitis, deep vein thrombosis, venous wall degeneration (e.g. aneurysms), arteriovenous shunts, or non-thrombotic iliac vein obstruction raises the risk for venous insufficiency.[3],[4]

Lifestyle factors. Prolonged standing, sedentary lifestyle, smoking, and pregnancy are suspected risk factors for the development of varicose veins, and obesity raises risk for venous disorders.[5] Physical inactivity is associated with risk for chronic venous insufficiency and varicose veins in some, although not all studies.[2],[6],[7]

High estrogen states and pregnancy also contribute to increased risk for developing venous insufficiency.

Klippel-Trenaunay-Weber syndrome. This rare congenital condition occurs due to an abnormal or absent deep venous system and results in a triad of extensive unilateral varicose veins, limb hypertrophy, and one or more port-wine stains.

Treatment

Initial conservative management is recommended for most patients. Bed rest, leg elevation, and compression stockings or bandages improve blood flow, reduce inflammation and edema, and compress dilated veins.

Leg elevation above the level of the heart for 30 minutes three or four times per day increases blood flow velocity, thus improving cutaneous microcirculation, and reduces edema in patients with chronic venous disease.

Exercise, such as daily walking and progressive resistance exercise up to three times per week, contributes to improvement in hemodynamic parameters and function. When combined with usual care such as compression, exercise has been shown to improve venous leg ulcer healing at 12 weeks

Compression stockings act by decreasing venous pressure and reflux. T

Several drug therapies have been used. Diuretics may be used in patients with severe edema resulting from medical conditions that exacerbate lower extremity symptoms. Oral antibiotics may be used to accelerate the healing of venous ulcers.

Venous ablation by injection sclerotherapy is useful in some patients with varicose veins for whom conservative therapies have failed. Laser therapy is the only option for treatment of telangiectasias that are too small for injection.

Several surgical options are available and have high success rates. These include venous ligation with or without stripping, endovenous catheter ablation, and valvular reconstruction.

Madelena Tapliga

MSc Clinical Nutritionist, accredited Nutritionist of UK from Association for Nutrition (AfN)

Herbal Medicine

MLD therapist

To schedule an appointment, call 07947887043 or click here to use our online form.

References

  1. Criqui MH, Jamosmos M, Fronek A, et al. Chronic venous disease in an ethnically diverse population: the San Diego Population Study. Am J Epidemiol. 2003;158(5):448-56.  [PMID:12936900]
  2. Lee AJ, Evans CJ, Allan PL, et al. Lifestyle factors and the risk of varicose veins: Edinburgh Vein Study. J Clin Epidemiol. 2003;56(2):171-9.  [PMID:12654412]
  3. Browse NL. The etiology of venous ulceration. World J Surg. 1986;10(6):938-43.  [PMID:3798942]Back to Citation
  4. Browse NL, Burnand KG. The cause of venous ulceration. Lancet. 1982;2(8292):243-5.  [PMID:6124673]
  5. MacKay D. Hemorrhoids and varicose veins: a review of treatment options. Altern Med Rev. 2001;6(2):126-40.  [PMID:11302778
  6. Jawien A. The influence of environmental factors in chronic venous insufficiency. Angiology. 2003;54 Suppl 1:S19-31.  [PMID:12934754]Back to Citation
  7. Brand FN, Dannenberg AL, Abbott RD, et al. The epidemiology of varicose veins: the Framingham Study. Am J Prev Med. 1988;4(2):96-101.  [PMID:3395496]Back to Citation

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Non surgical fat reduction

Ultrasonic cavitation, or ultrasound cavitation, is a cosmetic procedure that’s used to break apart fat deposits in your body. The treatment is an effective, less invasive alternative to liposuction, and relies on ultrasound technology to break apart fat cells. Fat cells then break apart from each other and are dislodged from your dermal layers. The ultrasound energy transmits through the skin, creating rapid pressure changes that cause the fat cells to break down while leaving surrounding tissues unharmed

What is ultrasonic cavitation treatment?

Ultrasonic cavitation, also called ultrasonic lipolysis, is a body contouring treatment that is used to remove fat deposits under your skin.

This is the most advanced 40K ultrasound cavitation technology, which can reach the fat body in depth and has the superiority of targeting and positioning RF output. The fat cell tissue can generate heat friction heat of the cell body in a fast and active state, and the local temperature rises. elies on ultrasound technology to break apart fat cells

Ultrasound cavitation causes fat emulsification, destroys the fat cell membrane, releases fat components, converts it into easily removable substances through sweat glands, liver and intestine circulation, and lymphatic system, and finally excretes through the urine.

Ultrasonic cavitation is different than other similar treatments, like ultrasound liposuction, because it doesn’t require any incisions. This means recovery is easier, and is not painful.

This is a risk-free process that avoids scars, discomfort, and downtime and is considered a safe alternative to liposuction. Ultrasound produces a powerful pressure wave that targets the fat cell membrane.

One of the the purpose of the ultrasound cavitation machine is to help weight loss. Ultrasound cavitation is a relatively new technique used primarily for the reduction of fat. The machine use sound waves and heat waves to help reduce cellulite and fat in the body.

After a few days, the fat cells are absorbed by your lymphatic system and drained as waste from your body.

What to expect after ultrasonic cavitation

After ultrasonic cavitation, you should be able to stand up and drive yourself home.

Pain and bruising are usually minimal. You’ll be instructed to hydrate as much as possible after the procedure to help your body flush the fatty cells through your lymphatic system.

But don’t expect to see results right away. Right after your appointment, your body might feel puffy or swollen. It takes time for your body to break down and dissolve the fat cells that have been dislodged.

You may also require repeated treatments to see visible results. Most candidates for this treatment see their final result within 6 to 12 weeks. On average, treatment requires 1 to 6 visits for visible results.

Results of this treatment are permanent, as long as you maintain a healthy diet and exercise. If you have a sedentary lifestyle, fat deposits may return to areas that have been treated

How much body area is treated during the procedure?

A one-hour treatment can cover a medium-sized area of your body, such as the belly, inner or outer thighs, buttocks, or your back. Smaller areas such as the chin or upper arm can be treated together. Multiple treatments on the same area are recommended for maximum effectiveness. Extra belly fat, for example, may need 3-6 treatments, while larger areas will need more.

Does ultrasonic cavitation results in saggy skin?

While some rapid weight-loss treatments can result in sagging skin, Ultrasonic Cavitation has a firming effect on the skin and muscle tissue, including loose skin from previous weight loss efforts. Actual results will vary.

Preparing for ultrasonic cavitation therapy

To prepare for your appointment,

During the consultation:

  1. Anthropometric measurements: a series of quantitative measurements of the muscle, bone, and adipose tissue used to assess the composition of the body. The core elements of anthropometry are height, weight, body mass index (BMI), body circumferences (waist, hip, and limbs), and skinfold thickness. These measurements are important because they represent diagnostic criteria for obesity, which significantly increases the risk for conditions such as cardiovascular disease, hypertension, diabetes mellitus, and many more. Additionally, anthropometric measurements can be used as a baseline for ultrasonic cavitation therapy and to measure the progress of fitness. 

Make sure that you disclose the following to your consultant before/during your appointment:

  1. any medical conditions you have
  2. any herbal supplements you take
  3. any medication that you’ve been prescribed
  4. Avoid drinking alcohol for at least 48 hours before your appointment.

You may also be advised to avoid nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, in the 2 weeks leading up to your procedure.

Drink plenty of water before and after your treatment so that your body can flush out fat deposits quickly.

This Treatment Can Be Used For:

  1. Weight Loss & Long Term Weight Management 
  2. Spot reducing areas of fat you struggle to lose through diet & exercise
  3. Lifestyle change 

Attention! This Treatment Cannot Be Used For:

1 Pregnant women or women during in menses.

  1. Epileptic.
  2. oncology patients
  3. chronic wounds
  4. Acute inflammation/post surgery/abdominoplasty
  5. heart and vascular disease, diabetes, acute illness, kidney failure
  6. female on period
  7. Who has the genetic hypersensitivity.
  8. In addition, medical implants in the body will make you untreated. These may include cochlear implants, pacemakers, and the like.

Benefits Of The Treatment: 

  1. Improved Appearance & Confidence Levels 
  2. Increased Energy
  3. Ideal for those who haven’t got time to spend hours in the gym
  4. Health Benefits 
  5. New Start for anyone who wants an achievable Weight Management Journey

Madelena Tapliga

MSc Clinical Nutritionist, accredited Nutritionist of UK from Association for Nutrition (AfN)

Herbal Medicine

MLD therapist

References

Casadei K, Kiel J. Anthropometric Measurement. [Updated 2020 Apr 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537315/

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How we age is not down to luck or genes! it is up to you

Key players for good health.

Food is medicine, and our diets play a significant factor in our body’s natural regeneration cycles.

Nutritional therapy aims to support the body in a number of ways so that problems resolve themselves. Drugs, on the other hand, are designed, usually to block or boost a single compound that is causing a problem- such as too much cholesterol or stomach acidity, or not enough serotonin or insulin.

This make nutrition and other lifestyle changes particularly suitable for encouraging healthy ageing, because ageing never involves juts one thing going wrong at a time

The important components of a cell

Mitochondria

Energy is generated in the body in the mitochondria, also releases damaging oxidants. The oxidants that are by products can damage tissue in the cells, so cells need a good supply of antioxidants to “snuff”them out.

To keep the mitochondria, working properly, we all produce as essential compound in the liver, called CoQ10, which can also disarm dangerous oxidants, because it is an antioxidant as well,

As your ageing body start, the wall of the mitochondria, becomes leakier, hence allowing oxidants to escape into the cells where they can cause damage especially to the DNA.

Mitochondria needs B vitamins and Co Q10 to function and antioxidants to control oxidants.

DNA

Your DNA is constantly under attack from the oxidants, however, some of them coming from mitochondria and others from external sources such as cigarette smoke, ultraviolet light and radiations

Cells make proteins using DNA as the blueprint. Therefore, damage to DNA speeds up ageing because it means that instruction fro proteins manufacture by the ribosome, can become garbled. Much of our body is made up of proteins- from our muscles to the enzymes that speed up chemical response. Nucleus contains the DNA genetic code. Needs vitamins, especially, C, D and E, zinc and magnesium.

DNA damage ( in the form of mutation) can also have another very harmful effect- it makes cancer more likely by knocking out genes that are designed to kill off cells before they start growing out of control. Without a good supply of a range of minerals and vitamins, your risk of faulty proteins and cancer goes up.

Telomeres

The telomeres sit right at either end of each chromosome where, rather like the plastic caps to protect the ends of shoelaces from fraying, they prevent the chromosomes from damage when the cell pulls apart down the middle to divide into two. Telomeres are markers of healthy ageing. Need B vitamins and antioxidants, vitamins A, C and E.

Lysosomes

One of their jobs is to break downs any of those damaged proteins created by faulty before they start to accumulate, so the proteins are broken downs into their amino acids, which are then reused. Lysosomes are also designed to get rid of harmful chemicals, both those we consume and by “eating”them up with enzymes. Lysosomes are part of the system that encourages unhealthy cells to commit suicide if they seem to be growing out of control. Left unchecked this leads to cancer. Unfortunately, there are many chemicals that lysosomes cannot break downs,

Cell membrane

A powerful factor controlling a cell is what is going on in the cells around it, and information about this has to come in through the membrane. Hence, the membrane acts partly like our senses, constantly responding to what is going on outside and feeding it back inside. It is made up of a mix of fats and proteins arranged so that certain molecules are allowed in but others are not. Drugs and other chemicals, along with nutrients, can enter through channels built of proteins

Essentially, this wall is made up of what we choose to eat; so not getting enough of the right ingredients can therefore mean that your cell membranes will function less efficiently. Along with the protein, the cell membrane is composed of phospholipids and essential fats, which can be found, among other sources, in eggs and fish. Needs various types of fats, such as omega 3, cholesterol and phospholipids

Drugs and vitamins

The drugs ca lower vitamin and mineral levels.

For example that cholesterol lowering statins also cut the production of powerful antioxidant called CoQ10, which is needed by your mitochondria to produce energy. That is why so many people on statins feel tired. Diuretics to lower blood presure rush various minerals and vitamins out of the body, including vitamin C, calcium, potassium and magnesium, all of which are involved in controlling blood pressure!

Ace inhibitors , also used for hypertension , cut available zinc which is needed by the immune system and to make testosterone, so no more sex drive.

SSRI antidepressant, which lower thyroid hormones, but these same hormones are involved in regulating energy and mood! As a result, most people on antidepressant find they work less over time,but when they try to quit, many absolutely awful, with serious depleted serotonin levels and thyroid problems to boot ( Suzy Cohen, 2011)

Keeping your mithocondria, DNA and the rest of the key players working as well as possible is an essential part of the secrets of healthy ageing.

The best ways of doing this are with certain types of exercise and a diet that is specifically designed to help with the changes that come with ageing, along with supplements where necessary.

Madelena Tapliga

MSc Clinical Nutritionist, accredited Nutritionist of UK from Association for Nutrition (AfN)

Herbal Medicine

MLD therapist

References

Cohen, S. (2011). Drug Muggers: Which Medication are Robbing your body of essential Nutrients.

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Rheumatoid arthritis (RA) is a systemic, debilitating, chronic inflammatory autoimmune disorder affecting approximately 1% of the world population (1). The disease severely impacts quality of life with increased morbidity and reduced life expectancy.

With undefined pathogenesis, different studies report a blend of environmental and genetic factors responsible for full expression of the disease. The shared epitopes coded by human leukocyte antigen (HLA) alleles, non-HLA genes, epigenetic factors, and differentially glycosylated proteins are considered significant risk factors for progression of RA (2-3). Elevated levels of rheumatoid factors (RF) (4), anti-cyclic citrullinated peptide autoantibodies (5) and anti-mannose-binding lectin autoantibodies are some examples of autoimmune responses by RA patients. These factors, however, contribute approximately 50% to the risk of development of RA while the rest may be contributed by host–environment interactions (6). Environmental factors responsible for development of RA may present and act even before disease symptoms become apparent. Early environmental factors such as high birth weight promotes chances of development of RA and early start of breast feeding reduces chances of development of RA (7). Other environmental factors such as smoking and infectious diseases also pose risk of developing RA (8)

Early recognition and treatment of RA is complicated because of heterogeneous nature of the disease. No biomarker is available to detect the early onset of disease, and traditional biomarkers may not identify all patients that require early therapeutic interventions (9), and thus, the patients face severe complications with serious joint damage and disability. The first line of treatment for RA includes disease-modifying antirheumatic drugs (DMARDs) that suppress disease activity and reduce joint damages. Continuous administration of biologics being the only option for prolonged remission, however, this being expensive is still beyond the reach of most people in the urban and the rural sectors.

Furthermore, patients with RA generally complain of gastrointestinal tract problems particularly dyspepsia (bloating, postprandial fullness, nausea, early satiety, epigastric pain, and burning and belching), mucosal ulceration, and altered bowel habits (constipation/diarrhea) (10). Recently, Littman laboratory identified Prevotella copri significantly prevalent in RA patients than healthy controls providing the support that the “gut-joint axis” hypothesis is relevant for human rheumatic diseases and may lead to pathogenesis of RA (11). 

Dietary Interventions in RA

With the increasing evidence of altered microbiota in the gut of RA patients being responsible for pathogenesis as well as disease progression (12,13,14, it should be desirable for rheumatologists to advocate a supplemental “diet therapy” to RA patients. Various dietary plans for RA have been reported since longand are being repeatedly projected), such as medically supervised 7–10 days fasting ), vegan or Mediterranean diets (MDs)

Nutritional epidemiology has seen a shift away from single nutrient analyses to a complementary approach in the form of dietary pattern analysis (). Evaluating dietary patterns can provide a more holistic and clinically relevant approach to assessing diet-disease relations as nutrients are not eaten in isolation and synergistic effects of multiple components can have a concerted effect (15). Vegetarian-based dietary patterns are typically higher in fruits, vegetables, whole grains, nuts, seeds, and legumes, all of which are naturally higher in phytochemicals and some vitamins compared to non-vegetarian dietary patterns . A variety of vegetarian-based eating patterns exist based on the inclusion or exclusion of animal products. For example, individuals who omit all animal products are classically described as vegan, whilst those who include eggs and dairy products are referred to as lacto-ovo-vegetarian (LOV) . Consumption of these dietary patterns are protective against many chronic diseases, including coronary heart disease, type 2 diabetes mellitus (T2DM), some cancers, and are associated with lower all-cause mortality.

References

1. Gibofsky A. Overview of epidemiology, pathophysiology, and diagnosis of rheumatoid arthritis. Am J Manag Care (2012) 18(13 Suppl):S295–302.

2.Holoshitz J. The rheumatoid arthritis HLA-DRB1 shared epitope. Curr Opin Rheumatol (2010) 22(3):293. doi:10.1097/BOR.0b013e328336ba63

3. Rioux JD, Abbas AK. Paths to understanding the genetic basis of autoimmune disease. Nature (2005) 435(7042):584–9. doi:10.1038/nature03723

4. Eggert M, Zettl U, Neeck G. Autoantibodies in autoimmune diseases. Curr Pharm Des (2010) 16(14):1634–43. doi:10.2174/138161210791164144

5. Rantapää-Dahlqvist S, de Jong BA, Berglin E, Hallmans G, Wadell G, Stenlund H, et al. Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis. Arthritis Rheum (2003) 48(10):2741–9. doi:10.1002/art.11223

 6 Edwards CJ. Commensal gut bacteria and the etiopathogenesis of rheumatoid arthritis. J Rheumatol (2008) 35(8):1477–9.

7. Jacobsson LT, Jacobsson ME, Askling J, Knowler WC. Perinatal characteristics and risk of rheumatoid arthritis. BMJ (2003) 326(7398):1068–9. doi:10.1136/bmj.326.7398.1068

8.Edwards C, Cooper C. Early environmental factors and rheumatoid arthritis. Clin Exp Immunol (2006) 143(1):1–5. doi:10.1111/j.1365-2249.2005.02940.x

9.Gonzalez-Alvaro I, Ortiz AM, Seoane I, García-Vicuña R, Martínez C, Gomariz R. Biomarkers predicting a need for intensive treatment in patients with early arthritis. Curr Pharm Des (2015) 21(2):170–81. doi:10.2174/1381612820666140825123104

10. Wolfe F, Kong SX, Watson DJ. Gastrointestinal symptoms and health related quality of life in patients with arthritis. J Rheumatol (2000) 27(6):1373–8.

11.Scher JU, Sczesnak A, Longman RS, Segata N, Ubeda C, Bielski C, et al. Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis. Elife (2013) 2:e01202. doi:10.7554/eLife.01202

12Vaahtovuo J, Munukka E, Korkeamäki M, Luukkainen R, Toivanen P. Fecal microbiota in early rheumatoid arthritis. J Rheumatol (2008) 35(8):1500–5.

13. Toivanen P. Normal intestinal microbiota in the aetiopathogenesis of rheumatoid arthritis. Ann Rheum Dis (2003) 62(9):807–11. doi:10.1136/ard.62.9.807

14. Scher JU, Sczesnak A, Longman RS, Segata N, Ubeda C, Bielski C, et al. Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis. Elife (2013) 2:e01202. doi:10.7554/eLife.01202

15 Jacobs DR Jr, Gross MD, Tapsell LC. Food synergy: an operational concept for understanding nutrition. Am J Clin Nutr. 2009;89(5):1543S–8S. [PMC free article] [PubMed] [Google Scholar]

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  1. Madelena has been my nutritionist since February, and I feel extremely grateful to have met her. She is a kind, welcoming and has vast knowledge about her work.

    For many years I have suffered with medical issues. one of my biggest challenges I was having was with my feet and not being able to walk properly as I was always in constant pain.

    Doctors where only able to prescribe an assortment of medication which only masked the pain and led to more issues.

    From meeting Madelena, she was able to regularise my eating habits, advise me on what and when to eat and certain supplements and vitamins to take.

    At first it was very difficult to stop eating the foods I’ve enjoyed for most of my life, but once again, she was understanding of this and worked with me to cut them down and help me overcome this.

    Within a month I could feel the difference this was having on me. Movement was becoming more easier; my weight gain was reduced, and my overall well-being was improved. Although, I still take medication at present, it is dramatically decreased making the associated issues I was experiencing from the medication cease.

    I am so grateful to Madeleina as she has given me back hope.

    If you are thinking about using her services, I totally recommend her

    Reply
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